Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Karolinska Institutet | OTHER |
| Kaunas University of Technology | OTHER |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Success of the hip arthroplasty depends on the measures that optimize perioperative conditions.It is planned to evaluate semi-closed loop system in the hip arthroplasty surgery.
Success of the total hip arthroplasty depends on the measures that optimize perioperative conditions. They increase the emotional stress of the staff and error probability. It is planned to evaluate semi-closed loop infusion system, its adaption for infusion application's influence to near and far treatment outcomes done by prospective randomized clinical trial. This is done by performing total hip arthroplasty. It's expected to evaluate the semi-closed loop system's influence on the doctor's emotional tension during the decision making.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| semi-closed system group | Experimental | Semi-closed loop infusion system tactic. Programmed iv fluid and blood infusion system ,,Belmont Rapid Infuser" and programmable syringe pump for adrenaline infusion. |
|
| control group | Experimental | Routine infusion therapy tactic |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Semi-closed loop infusion system tactic. | Procedure | Semi -closed loop infusion system tactic.Use volume loading test twice (before surgery and 12hrs postoperatively). Computer provides advisory hypotension treatment algorithm. Computer provides advisory anemia treatment algorithm. Programmed iv fluid and blood infusions system ,,Belmont Rapid Infuser" and programmable syringe pump for adrenaline infusion. |
| Measure | Description | Time Frame |
|---|---|---|
| The efficiency of semi-closed loop infusion system | Determine the ratio of doctor's approved and rejected computer suggestions | Before the surgery and 12 hrs postoperatively |
| Measure | Description | Time Frame |
|---|---|---|
| Perioperative blood loss | Non-invasive measurement of Hb (Masimo technology). Laboratory hemoglobin determination, evaluation of the bleeding volume | Before (baseline) the surgery,during surgery and 24hrs postoperatively |
| Coagulation activity |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Andrijauskas Audrius, PhD | Vilnius University | Principal Investigator |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D015207 | Osteoarthritis, Hip |
| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| Routine infusion therapy tactic | Procedure | Routine re-hydration bolus before surgery. Routine treatment of hypotension. Routine treatment of anemia. |
|
Coagulation activity is investigated thromboelastically
| Before (baseline) the surgery and 24hrs postoperatively |
| Infused fluid and red blood cell volume | Repeated rehydration bolus (sol.Ringeri 2,5ml/kg), supportive fluid infusion (sol.NaCl 0,9% 1,5 ml/kg/hrs); evaluation of signs of anemia intolerance if Hb < 110 g/l | Before the surgery and 24hrs postoperatively |
| Wound healing | Evaluation of wound tissue condition, measurement of drainage fluid volume | Within 6 days postoperatively |
| Dosage physical exercise sample | Timed up and go test | Within 6 days postoperatively |
| Haemodynamic stability | Invasive measurement of arterial blood pressure | Before (baseline) the surgery and 12 hrs postoperatively |
| Complications | Registration of all complications | Within 6 days postoperatively |
| D012216 |
| Rheumatic Diseases |