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The purpose of this study is to determine whether an operative hemodynamic optimization using the plethysmographic variability index during orthopedic surgery could decrease the length of hospital stay and the postoperative morbidity.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PVI group | Other | Fluid optimisation using PVI |
|
| Control group | No Intervention | Standard care using a hemodynamic protocol during general anesthesia |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Plethysmographic variability index | Device |
|
| Measure | Description | Time Frame |
|---|---|---|
| Length of hospital stay after knee or hip arthroplasty | Surgeons, blinded to the group allocation, are the postoperative care providers who decide the length of hospital stay. | Real length of hospital stay expressed as number of day (maximum 60 days) |
| Measure | Description | Time Frame |
|---|---|---|
| Troponin value | Postoperative Day 1 and Day 3 | |
| Creatinine value | Postoperative Day 1 and Day 3 | |
| Arterial Lactate |
| Measure | Description | Time Frame |
|---|---|---|
| Medico economic evaluation | Participants will be followed for the duration of hospital stay, an expected average of 1 week, until postoperative day 60 |
Inclusion Criteria:
Non Inclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Caen University Hospital | Caen | 14 000 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26537815 | Derived | Fischer MO, Daccache G, Lemoine S, Tavernier B, Compere V, Hulet C, Bouchakour CE, Canevet C, Gerard JL, Guittet L, Lorne E, Hanouz JL, Parienti JJ. The OPVI trial - perioperative hemodynamic optimization using the plethysmographic variability index in orthopedic surgery: study protocol for a multicenter randomized controlled trial. Trials. 2015 Nov 4;16:503. doi: 10.1186/s13063-015-1020-7. |
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| 1 hour after end of surgery |
| Postoperative cardiac complications | Participants will be followed for the duration of hospital stay, an expected average of 1 week, until postoperative day 60 |
| Theorical length of hospital stay after knee or hip arthroplasty | Evaluation twice per day starting day 3 until up day 60. A check list was used by an independant investigator to define the theorical date of end hospitalisation, from day 3 until day 60 | Theorical length of hospital stay expressed as number of day (maximum 60 days) |