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A randomised back to back study comparing cap and Endocuff to detect adenomas during colonoscopy
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Endocuff assisted colonoscopy | Active Comparator | Participants are randomised to undergo first either with Endocuff or cap assisted colonoscopy during colonoscopy. |
|
| Cap assisted colonoscopy | Placebo Comparator | Participants are randomised to undergo first either with Endocuff or cap assisted colonoscopy during colonoscopy. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Endocuff | Device | It is a randomised back to back study to compare cap and Endocuff to detect adenoma in colonoscopic examination |
|
| Measure | Description | Time Frame |
|---|---|---|
| Adenoma miss rate | Comparison of adenoma miss rate between cap ( CAC) and Endocuff assisted colonoscopy(E | 1 day |
| Measure | Description | Time Frame |
|---|---|---|
| Mean adenoma per procedure | Difference in mean adenomas detected per procedure (MAP) between EAC and CAC. | 1 day |
| Endocuff or cap exchange | Number of times Cap or Endocuff are removed to complete the procedure |
| Measure | Description | Time Frame |
|---|---|---|
| comparison of surveillance intervals | To compare any surveillance interval difference between CAC and EAC | Once histology is available usually takes 10-14 days |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Brian P Saunders, MD | St Mark's Hospital, Northwest London Hospitals NHS Trust | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| NorthWest London Hospitals - NOrthwick park hospital | Harrow | Middlesex | HA1 3UJ | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31836474 | Derived | Rameshshanker R, Tsiamoulos Z, Wilson A, Rajendran A, Bassett P, Tekkis P, Saunders BP. Endoscopic cuff-assisted colonoscopy versus cap-assisted colonoscopy in adenoma detection: randomized tandem study-DEtection in Tandem Endocuff Cap Trial (DETECT). Gastrointest Endosc. 2020 Apr;91(4):894-904.e1. doi: 10.1016/j.gie.2019.11.046. Epub 2019 Dec 10. |
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| ID | Term |
|---|---|
| D003110 | Colonic Neoplasms |
| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
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It is a randomised back to back study to compare the performance of cap assisted colonoscopy (CAC) and Endocuff assisted colonoscopy (EAC)
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| cap assisted colonoscopy (CAC) | Device | cap assisted colonoscopy (CAC) |
|
| 1 day |
| Ceacal intubation and withdrawal time | Comparison of caecal intubation and withdrawal time | 1 day |
| miss rate of advanced polyps | Comparison of miss rates of advanced adenomas, serrated polyps and proxima polyps between CAC and EAC | 1 day |
| Comfort score | Comparison of patient comfort score between CAC and EAC | 1 day |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |