Endocuff-assisted Versus Cap-assisted Versus Standard Colonoscopy

Endocuff-assisted Versus Cap-assisted Versus Standard Colonoscopy for Adenoma Detection: A Randomized Controlled European Multicenter Study

Comparison of Endocuff-assisted, Cap-assisted and Standard colonoscopy for assessment of the adenoma detection rate (ADR)

The Endocuff is a medical device, approved in 2012 by the American Food and Drug Administration, which was also authorized by the European Agency for the Evaluation of Medicinal Products. The aim of the cuff is to optimize the view of the colonic mucosa. There is also a transparent cap on the market, which is used in colonoscopy for a better evaluation of the mucosa and polyp detection. The goal of this project is to conduct a prospective randomized trial for clarification of the hypotheses, whether the usage of the Endocuff increases the detection rate of adenomas compared to the transparent cap or compared to standard colonoscopy.

Inclusion Criteria:

• Colonoscopy independent from indication
• Age ≥ 18
• Patient is able to provide informed consent for the procedure

Exclusion Criteria:

• Inflammatory Bowel Disease stenosis
• Pregnant of nursing patient
• Acute diverticulitis
• Active Inflammatory Bowel Disease
• Age ≤ 18
• Coagulation disorder (INR>1.4 , Thrombocytes < 50000/µl)