The Nutritional Health for the Elderly Reference Centre S... | NCT03240952

Studies
The Nutritional Health for the Elderly Reference Centre Study (NHERC Study)

NCT03240952

Sponsor

Abbott Nutrition

Status

Completed

Last Update Posted

Apr 15, 2020Actual

Enrollment

400Actual

Phase

Not provided

Conditions

Malnutrition

Interventions

Not provided

Countries

Singapore

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Apr 2020

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Aug 30, 2017Actual

Primary Completion Date

May 28, 2018Actual

Completion Date

Jul 26, 2018Actual

First Submitted Date

Aug 1, 2017

First Submission Date that Met QC Criteria

Aug 4, 2017

First Posted Date

Aug 7, 2017Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Apr 13, 2020

Last Update Posted Date

Apr 15, 2020Actual

Name	Class
Changi General Hospital	OTHER
SingHealth Polyclinics	OTHER

Description Module

Brief Summary

Elderly are at greater risk of dietary insufficiency due to age-related increases in nutrient requirements concomitant with a reduction in energy requirements, decreases in appetite and energy intake. Currently there is a gap in knowledge of the factors that are associated with malnutrition in the elderly in Singapore. In addition, there is no "reference" database on anthropometric measurements and biochemical indices for elderly with a range of nutrition status in Singapore. Thus, the objectives of this cross-sectional study are to examine factors influencing nutritional status and to determine the reference values for anthropometric and biochemical measurements related to nutritional status for community-dwelling elderly in Singapore.

Detailed Description

This is a cross-sectional study. Measurements will be taken at baseline for elderly with normal nutrition (n = 400) and elderly who are at risk of under nutrition (n = 800).. These measurements will be used to examine factors influencing nutritional status and to create a "reference" database for anthropometric and biochemical measurements related to nutritional status for use in clinical practice.

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

400Actual

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
MUST	Malnutrition risk using Malnutrition Universal Screening Tool	Baseline

Secondary Outcomes

Measure	Description	Time Frame
Body weight, fat mass, fat free mass	Body weight, fat mass, fat free mass in kilograms will be measured using Tanita MC-780	Baseline
Pre-albumin	Pre-albumin in mg/dL will be measured using Cobas

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Male or female participant aged ≥65 years.
Community-dweller, i.e. not staying in a residential intermediate and long-term care (ILTC) service institution.
Participant is being discharged home directly (applicable for hospital cohort).
Participant is community ambulant with or without aid.
Participant does not have any chronic disease(s) or has stable chronic disease(s) including hypertension, chronic obstructive pulmonary disease, and cardiovascular disease in the opinion of the Study Physician, at study entry.
Participant has voluntarily signed and dated an informed consent form (ICF), approved by an Institutional Review Board (IRB) and provided authorization prior to any participation in the study.
Participants will be able to communicate and follow instructions.
Participant is able to consume food and beverages orally.

Exclusion Criteria:

Participant has been diagnosed with dementia according to medical records.
Participant has been diagnosed with type 1 or type 2 diabetes according to medical records. (Note: This includes participant with controlled diabetes.)
Participant has any active infectious disease (such as tuberculosis, Hepatitis B or C, HIV infection) according to medical records.
Participant has been diagnosed with severe gastrointestinal disorders including celiac disease, short bowel syndrome, pancreatic insufficiency, or cystic fibrosis according to medical records.
Participant has been diagnosed with end stage organ or pre-terminal diseases or acute myocardial infarction within the last 30 days from the screening according to medical records.
Participant has malignancy according to medical records.
Participant has any other clinically significant medical condition, which in the investigator's opinion, makes him or her unsuitable for inclusion in the study.
Participant is taking part in another study that has not been approved as a concomitant study by the study team.

Accepts Healthy Volunteers

Yes

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

65 Years

Maximum Age

110 Years

Standard Ages

Older Adult

Study Population

This cross-sectional study will include 400 elderly with normal nutrition (MUST score: 0) and 800 elderly who are at risk of undernutrition (MUST score ≥ 1). Community-dwelling elderly recently discharged from the hospital as well as those who recently visited polyclinics in Singapore will be recruited for the study.

Sampling Method

Non-Probability Sample

Name	Affiliation	Role
Siew Ling Tey, Ph.D.	Abbott Nutrition Research & Development	Study Chair
Samuel TH Chew, MB.BCh.BAO	Changi General Hospital	Principal Investigator

Facility	Status	City	State	ZIP	Country	Contacts
Marine Parade Polyclinic		Singapore		440080	Singapore
Bedok Polyclinic

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
40849644	Derived	Husain FS, Tey SL, Huynh DTT, Oliver J, Baggs G, How CH, Chow WL, Cheong M, Aw TC, Chew STH, Tan NC. Aging and liver health: liver chemistries and associated factors in community-dwelling older adults. BMC Geriatr. 2025 Aug 23;25(1):658. doi: 10.1186/s12877-025-06329-2.
34895351	Derived	Ong RHS, Chow WL, Cheong M, Lim GH, Xie W, Baggs G, Huynh DTT, Oh HC, How CH, Tan NC, Tey SL, Chew STH. Associations between socio-demographics, nutrition knowledge, nutrition competencies and attitudes in community-dwelling healthy older adults in Singapore: findings from the SHIELD study. J Health Popul Nutr. 2021 Dec 11;40(1):52. doi: 10.1186/s41043-021-00277-4.

ID	Term
D009748	Nutrition Disorders
D009750	Nutritional and Metabolic Diseases