Sedation During Pediatric Diagnostic Gastrointestinal Endoscopy Gastrointestinal Endoscopy

Propofol-Ketamine vs. Propofol-Fentanyl for Sedation During Pediatric Diagnostic Gastrointestinal Endoscopy

comparison between propofol-fentanyl and propofol-ketamine for sedation in pediatric diagnostic gastrointestinal endoscopy.

It is a prospective double blinded controlled study that will be carried out on 60 pediatric patients undergoing GIT endoscopy; they will be divided into two groups of 30 patients each:- Group I (PF): will receive 0.5 µg/ kg fentanyl + 2 mg/ kg propofol IV. Group II (KF): will receive Ketofol (1 ketamine: 4 propofol) 0.5 mg/kg ketamine + 2 mg/kg propofol IV.

Inclusion Criteria:

• Pediatric patients undergoing diagnostic GIT endoscopy
• ASA I-II

Exclusion Criteria:

• Emergency endoscopy
• Respiratory infection and hyperactive airways
• History of serious adverse effects related to anesthetics (e.g. allergic reactions), a family history of reactions to the study drugs
• Morbid obesity, and neuropsychiatric disorders