Follow Up Study for Treatment of Parkinson's Disease With Subthalamic Deep Brain Stimulation

Long Term Study of Subthalamic Deep Brain Stimulation for Parkinson's Disease

This study aims to evaluate the long term effect of deep brain stimulation in the the subthalamic nucleus (STN) in patients with Parkinson's disease.

Inclusion Criteria:

• Idiopathic Parkinson's disease
• Disease duration longer than 15 years
• Had STN deep brain stimulation implant more than 10 years
• Available and willing to be followed-up according to study protocol

Exclusion Criteria:

• Patients with serious diseases such as tumor, sever liver or kidney dysfunction were not selected in the clinical trials
• Epilepsy
• Pregnant female
• History of severe neuropsychiatric disease
• Patients are taking part in other clinical trials in recent several months