Immunosuppression's Long Term Impact on Anti-tumoral Oversight in Kidney Transplantation

Immunosuppression's Long Term Impact on Anti-tumoral Oversight in Kidney Transplantation

Cancer is a well known complication about long term transplantation. Cancer outcomes are due to the immunosuppressive treatment that prevents transplanted people from rejection. By lowering the effectiveness of the immune system, immune cells are no longer able to seek and destroy cancer cells.

The goal here is to study immunes cells population of people that were transplanted 10 years ago and are now treated either by a corticosteroid - azathioprine association, or only by cyclosporine A.

Inclusion Criteria:

• Patients over 18
• Patients with kidney transplantation for 10 year
• Patients with stable renal function (less than 20% creatinine variation during the last 12 months)
• Patients treated either by a corticosteroid - azathioprine association or cyclosporine A
• Patients giving his agreement
• Patients legally free

Exclusion Criteria:

• Patients under 18
• Patients under legal protection
• Pregnant women, or of age to get pregnant