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| ID | Type | Description | Link |
|---|---|---|---|
| ID-RCB | Other Identifier | 2017-A00918-45 |
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failure to recruit
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Pain is complex phenomenon misunderstood in spite of medical progress and neurosciences. That's why the relief of chronic pain is only partial for a lot of infection as arthrosis, chronic back pain, headaches or neuropathic pain. Certain situations bring to relive pain sensation. Investigators were interested to former burned. They wonder about somatic memory and unconscious of acute.
It is a comparative and monocentric study. There are two groups. On the one hand, there is the former burned and, on the other hand, healthy volunteers. While they thought to painful memory or not, functional Magnetic Resonance Imaging (fMRI) will be performed. Then, investigators compare two functional Magnetic Resonance Imaging (fMRI).
Main objective of this study is link up between brain activity by functional Magnetic Resonance Imaging (fMRI) and acute pain memory.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| patients | Experimental | Patient who was burned will have fMRI. |
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| control group | Active Comparator | Healthy volunteers (control group) will have fMRI. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| fMRI | Other | During fMRI, patients and control group will have to thought to seven painful memories, seven emotional memories not painful, seven neutral memories. At every memory there is control test. It is to count backwards. |
| Measure | Description | Time Frame |
|---|---|---|
| BOLD (blood-oxygen-level dependent) signal between painful memories | Correlation between BOLD measured by functional Magnetic Resonance Imaging (fMRI) and every conditions: painful memories, emotional memories not painful, neutral memories and control test. | Months 3 |
| BOLD (blood-oxygen-level dependent) signal between emotional memories not painful | Correlation between BOLD measured by functional Magnetic Resonance Imaging (fMRI) and every conditions: painful memories, emotional memories not painful, neutral memories and control test. | Months 3 |
| BOLD (blood-oxygen-level dependent) signal between neutral memories | Correlation between BOLD measured by functional Magnetic Resonance Imaging (fMRI) and every conditions: painful memories, emotional memories not painful, neutral memories and control test. | Months 3 |
| BOLD (blood-oxygen-level dependent) signal between control test. | Correlation between BOLD measured by functional Magnetic Resonance Imaging (fMRI) and every conditions: painful memories, emotional memories not painful, neutral memories and control test. | Months 3 |
| Measure | Description | Time Frame |
|---|---|---|
| BOLD (blood-oxygen-level dependent) signal between control group for every conditions | Correlation between BOLD measured by functional Magnetic Resonance Imaging (fMRI) and groups for every conditions: painful memories, emotional memories not painful, neutral memories and control test. | Months 3 |
| BOLD (blood-oxygen-level dependent) signal between patients for every conditions |
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Inclusion Criteria:
For control group:
For former burned:
Exclusion Criteria:
For control group:
For former burned:
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| Name | Affiliation | Role |
|---|---|---|
| Jean-Claude GETENET, MD | Centre Hospitalier Universitaire de Saint Etienne | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Saint-Etienne | Saint-Etienne | 42055 | France |
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| ID | Term |
|---|---|
| D010146 | Pain |
| D002056 | Burns |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D014947 | Wounds and Injuries |
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Two groups: 20 patients and 20 healthy volunteers
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Correlation between BOLD measured by functional Magnetic Resonance Imaging (fMRI) and groups for every conditions: painful memories, emotional memories not painful, neutral memories and control test. |
| Months 3 |