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To observe the effects of hypogastric artery ligation on serum antimullerian hormone levels.
To measure and compare serum antimullerian hormone levels in patients who underwent hypogastric artery ligation/ hypogastric artery ligation+ hysterectomy and postpartum control. The procedures performed as an emergency life saving method during delivery. The reasons for hypogastric artery ligation/ hypogastric artery ligation+ hysterectomy were obstetric hemorrhage mainly uterine atony.
The serum levels of antimullerian hormone were measured 6 months after the operations and compared with matching postpartum controls. Serum levels of FSH, LH, PRL and TSH were also measured 6 months after the operation. Further, antral follicle count measured along with the aforementioned blood tests.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hypogastric artery ligation (HAL) | Patients who underwent only hypogastric artery ligation performed during the delivery of their babies. Six months after the operation they will evaluated for their ovarian reserve via hormones and astral follicle count (AFC) |
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| HAL and hysterectomy | Patients who underwent both hypogastric artery ligation and hysterectomy performed during the delivery of their babies. Six months after the operation they will evaluated for their ovarian reserve via hormones and astral follicle count (AFC) |
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| Postpartum | Postpartum control group constituted of patients delivered baby without any complication and evaluated 6 months later. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| hypogastric artery ligation | Procedure | hypogastric artery ligation is the ligation of the internal iliac artery to stop bleeding related to obstetrics obstetric hemorrhage Hysterectomy is the removal of the uterus if bleeding can't stop by hypogastric artery ligation |
| Measure | Description | Time Frame |
|---|---|---|
| Ovarian reserve | To evaluate postoperative ovarian reserve using anti-mullerian hormones and other ovary related hormones including FSH,LH | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
All participants are females undergoing delivery of their baby
Patients who had hypogastric artery ligation and/or hysterectomy during their delivery. Control group is age-matched postpartum patients.
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| Name | Affiliation | Role |
|---|---|---|
| Alev Atıs, MD,ObGyn | Kanuni Sultan Suleyman Training and Research Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kanuni SSTRH | Istanbul | 34303 | Turkey (Türkiye) |
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| Label | URL |
|---|---|
| The effect of total abdominal hysterectomy on serum anti-Müllerian hormone levels: a pilot study | View source |
| Effect of internal iliac artery ligation on ovarian blood supply and ovarian reserve | View source |
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| ID | Term |
|---|---|
| D007044 | Hysterectomy |
| ID | Term |
|---|---|
| D013509 | Gynecologic Surgical Procedures |
| D013519 | Urogenital Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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