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The aim of this study is to assess the possible negative effects of uterine artery ligation on ovarian reserve markers and subsequent pregnancy outcomes
One of the most common surgical methods for preserving fertility is uterine artery ligation. It is simple to do and effective at reducing Postpartum hemorrhage after delivery . Additionally, it is rather safe and permits future childbearing for the patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| control group | underwent normal cesarean section without Postpartum hemorrhage after delivery |
| |
| case group | cases underwent bilateral uterine artery ligation after Postpartum hemorrhage or Intrapartum hemorrhage after cesarean section. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bilateral uterine artery ligation | Procedure | Bilateral UAL was done 2 cm under the Kerr incision (lower segment transverse). A 2-Vicryl absorbable suture (Ethicon, Neuilly-surSeine, France) was introduced from the anterior to posterior views of the myometrium 2-3 cm medial to the descending part of the uterine vessels within an avascular area in the broad ligament and tied. Following the surgery, the uterine tone and hemorrhage were managed. |
| Measure | Description | Time Frame |
|---|---|---|
| Ovarian reserve by anti-mullerian hormone | Anti-mullerian hormone (AMH) level will be determined using a two-sided immunoassay that will be enzymatically amplified (ELISA). AMH was recorded at 6, 12 and 24 months after bilateral uterine artery ligation. | 24 months after bilateral uterine artery ligation. |
| Measure | Description | Time Frame |
|---|---|---|
| Ovarian reserve by follicle stimulating hormone | follicle stimulating hormone (FSH) level will be determined using a two-sided immunoassay that will be enzymatically amplified (ELISA). FSH was recorded at 6, 12 and 24 months after bilateral uterine artery ligation. | 24 months after bilateral uterine artery ligation. |
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Inclusion Criteria:
Exclusion Criteria:
females aged from 20 to 35 years old with Postpartum hemorrhage or intrapartum hemorrhage after cesarean section who did not respond to medical therapy and performed successful bilateral uterine artery ligation for hemorrhage management.
Patients will be classified into two equal groups control group: underwent normal cesarean section without Postpartum hemorrhage, case group: cases underwent bilateral uterine artery ligation after Postpartum hemorrhage or intrapartum hemorrhage after cesarean section.
All patients will be subjected to the following clinical parameters assessment (age, cycle history, body mass index, parity, preceding treatment and/or surgery menstruation characteristics (quantity of menstruation and dysmenorrhoea) and endometrial biopsy.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ahmed M.E. Ossman | Tanta | Egypt |
the data will be available when requested
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|
| Ovarian reserve by antral follicle counts |
antral follicle counts were recorded at 6, 12 and 24 months after bilateral uterine artery ligation. |
| 24 months after bilateral uterine artery ligation. |
| Percent of subsequent pregnancy cases | patients were asked about their desire for pregnancy in the future The data of subsequent pregnancy cases following bilateral UAL primary were recorded and follow-up was done at 6, 12 and 24 months after BUAL. | 24 months after bilateral uterine artery ligation. |
| ID | Term |
|---|---|
| D006473 | Postpartum Hemorrhage |
| ID | Term |
|---|---|
| D007744 | Obstetric Labor Complications |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D011644 | Puerperal Disorders |
| D014592 | Uterine Hemorrhage |
| D006470 | Hemorrhage |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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