Weissella Cibaria JW15 Consumption and NK Cell Activity

Weissella Cibaria JW15 Consumption and NK Cell Activity

A The aim of this study was to investigate the impact of consuming Weissella cibaria (W. cibaria) JW15 supplementation isolated from Kimchi, Korea traditional fermented food, on natural killer (NK) cell activity and circulating levels of cytokines and immunoglobulin (Ig).

A randomized, double-blinded, placebo-controlled study was conducted on 100 nondiabetic subjects. Over an eight-week testing period, the probiotic group consumed 4 capsules (300 mg/capsule) containing 1 x 10^10 colony-forming units (cfu) of W. cibaria JW15 each day, whereas the placebo group consumed the same product without a probiotic.

Inclusion Criteria:

• Nondiabetic (fasting serum glucose concentration < 126 mg/dL)
• Subjects with 4,000-8,000 leukocyte counts

Exclusion Criteria:

• Constant consumption of any probiotic products
• Taking medicine related to inflammation within one month before screening
• Allergy to probiotics
• Lactose intolerance
• Diabetes
• History/presence of significant metabolic disease
• Acute or chronic disease requiring treatment
• Taking any medications