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The purpose of this study is to compare the 1: 1 I: E ratio VCV and the autoflow VCV in patients undergoing robot assisted laparoscopic prostatectomy
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1:1 I:E ratio VCV (Group I) | Experimental | volume controlled ventilation with 1:1 inspiratory to expiratory ratio After trendelenburg position, Tidal volume : 8ml/kg, inspiration:expiration ratio = 1:1, FiO2 = 0.5, maintain end tidal CO2 around 40±5 mmHg. Positive end expiratory pressure will not used. |
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| autoflow VCV (Group A) | Active Comparator | autoflow volume-controlled ventilation After trendelenburg position, Tidal volume : 8ml/kg, inspiration:expiration ratio = 1:2, FiO2 = 0.5, maintain end tidal CO2 around 40±5 mmHg. Positive end expiratory pressure will not used. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ventilation strategy 1 | Procedure | In Group I, after trendelenburg position, patients will be applied 1:1 ratio VCV.
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| Measure | Description | Time Frame |
|---|---|---|
| PaO2 | PaO2 analyzed by arterial blood gas analysis | 30 minutes after trendelenburg position |
| Measure | Description | Time Frame |
|---|---|---|
| PaO2 | 10 minutes after induction (T1), 30 minutes after trendelenburg position (T2), 60 minutes after trendelenburg position (T3), 10 minutes after supine position (T4) | |
| End tidal CO2 | 10 minutes after induction (T1), 30 minutes after trendelenburg position (T2), 60 minutes after trendelenburg position (T3), 10 minutes after supine position (T4) |
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Inclusion Criteria:
Exclusion Criteria:
Male patients undergoing robot assisted laparoscopic prostatectomy
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine | Seoul | 03722 | South Korea |
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participants, investicator, outcome assessors will be blinded for group allocation.
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| ventilation strategy 2 | Procedure | In group A, after trendelenburg position, patients will be applied autoflow VCV. - Tidal volume : 8ml/kg, inspiration:expiration ratio = 1:2, FiO2 = 0.5, maintain end tidal CO2 around 40±5 mmHg. Positive end expiratory pressure will not used. |
|
| peak airway pressure | 10 minutes after induction (T1), 30 minutes after trendelenburg position (T2), 60 minutes after trendelenburg position (T3), 10 minutes after supine position (T4) |
| blood pressure | 10 minutes after induction (T1), 30 minutes after trendelenburg position (T2), 60 minutes after trendelenburg position (T3), 10 minutes after supine position (T4) |
| Arterial blood gas analysis | pH, SaO2, Base excess | 10 minutes after induction (T1), 30 minutes after trendelenburg position (T2), 60 minutes after trendelenburg position (T3), 10 minutes after supine position (T4) |