Neuroprognostication Using Optic Nerve Sheath Diameter

Post Cardiac Arrest Neuroprognostication Using the Diameter of Optic Nerve Sheath Via Ocular ultRAsound

This study investigates the relationship between optic nerve sheath diameter and increased intracranial pressure and its effect on neurologic outcome in post-cardiopulmonary arrest patients.

This study involves patients who have experienced either an in-hospital or out-of-hospital cardiopulmonary arrest, and who meet the 2015 American Heart Association (AHA) inclusion/exclusion criteria for targeted temperature management [i.e., they are comatose or exhibit no meaningful response to verbal commands with return of spontaneous circulation (ROSC) after cardiac arrest]. After induction of hypothermia protocol after cardiopulmonary arrest (i.e., targeted temperature management), patients will undergo ocular ultrasound at three time points.

Inclusion Criteria:

• Patient ≥ 18 years of age
• Patient has experienced either an in-hospital or out-of-hospital cardiopulmonary arrest
• Patient is comatose or exhibits lack of meaningful response to verbal commands with return of spontaneous circulation (ROSC) after cardiopulmonary arrest
• Patient must meet all inclusion criteria as deemed by physician and the 2015 American Heart Association standards for targeted temperature management (TTM) following cardiopulmonary arrest

Exclusion Criteria:

• Patient < 18 years of age
• Patient does not meet inclusion criteria for targeted temperature management (TTM)
• Unable to obtain consent from Legal Authorized Representative (LAR)
• Patient has a Do Not Resuscitate (DNR) order or a Do Not Intubate (DNI) order at the time of consent
• Patient has uncontrollable bleeding
• Patient is able to follow verbal commands
• Patient has another medical condition creating increased ocular pressure, as deemed by physician