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To compare the postoperative analgesic effect and the intensity of motor block in different concentration ropivacaine plus fentanyl when used epidurally with a patient-controlled analgesia device after Cesarean delivery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A | Active Comparator | Group A patients received 0.08% ropivacaine plus 4 mcg /mL fentanyl |
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| Group B | Active Comparator | Group B patients received 0.08% ropivacaine plus 2mcg /mL fentanyl |
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| Group C | Active Comparator | Group C patients received 0.16 % ropivacaine plus 2 mcg /mL fentanyl |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ropivacaine | Drug | Compare different concentration of ropivacaine and fentanyl for elective Cesarean delivery post operative pain control. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change From Baseline in Pain Scores on the numeric rating scale | The investigators use numeric rating scale(0~10) for pain severity measurement, 0 for no pain, 10 is the most severe pain | The investigators measured numeric score changing at 5 different timing. The first is when arrival post-operative care unit, the second is when arrival post-operative care unit for 2 hours. And then 6,24,48 hours after operation. |
| Measure | Description | Time Frame |
|---|---|---|
| Change From Baseline in Patient satisfaction scale | Patient satisfaction scale (1~4), 1 for very satisfied, 2 for satisfied, 3 for fair, and 4 for unsatisfied | The investigators measured numeric score changing at 5 different timing. The first is when arrival post-operative care unit, the second is when arrival post-operative care unit for 2 hours. And then 6,24,48 hours after operation. |
| Measure | Description | Time Frame |
|---|---|---|
| Change From Baseline in modified Bromage scale | The investigators use modified Bromage scale for motor block evaluation. Modified Bromage scale(0~3), 0 for no motor block. 1 for inability to raise extended leg, able to move knees and feet. 2 for inability to raise extended leg and move knee, able to move feet. 3 for complete block of motor limb | The investigatorsmeasured numeric score changing at 5 different timing. The first is when arrival post-operative care unit, the second is when arrival post-operative care unit for 2 hours. And then 6,24,48 hours after operation. |
Inclusion Criteria:
Exclusion Criteria:
Only include pregnant female receiving elective Cesarean delivery and post-operative epidural analgesia
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| Name | Affiliation | Role |
|---|---|---|
| Hui-Fang Huang | Kaohsiung Medical University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kaohsiung Medical University Hospital | Kaohsiung City | 807 | Taiwan |
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| ID | Term |
|---|---|
| D000077212 | Ropivacaine |
| D005283 | Fentanyl |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
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All patients were received epidural anesthesia with 2% Lidocaine and patient-controlled epidural analgesia (PCEA) for post- operative pain control. PCEA randomly allocated into three groups. Group A patients received 0.08% ropivacaine plus 4 mcg /mL fentanyl, Group B patients received 0.08% ropivacaine plus 2mcg /mL fentanyl, and Group C patients received 0.16 % ropivacaine plus 2 mcg /mL fentanyl. Dermographic data, dosage of PCEA during first 48 hours post-operation,NRS scores, patient satisfaction and the intensity of motor block will be recorded and analyzed.
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Participant do not know which formula they are receive. Nor do the daily care providers.
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| Fentanyl | Drug | Compare different concentration of ropivacaine and fentanyl for elective Cesarean delivery post operative pain control. |
|
| D000588 |
| Amines |
| D010880 | Piperidines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |