Clinical Value of Molecular Genetic Analyzes in Gynecological Malignomas

Clinical Value of Molecular Genetic Analyzes in Gynecological Malignomas

The aim of the planned research project is to find out the clinical significance of molecular genetic analyzes in gynecological malignomas. In particular, it will be investigated how the knowledge of a molecular-genetic finding affects the therapeutic decision of the physician. Furthermore, genetic changes in the tumor tissue will be compared with the changes in CTCs, DTCs and cfDNA.

Inclusion Criteria:

• Patients with a solid tumor disease
• The presence of a molecular genetic diagnosis of the tumor tissue from practice for human genetics
• Age > 18 years
• informed consent

Exclusion Criteria:

• life expectancy <12 months or worse general condition (Karnofsky <70)