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eligible teeth will be randomly divided into two groups to be treated with incomplete caries excavation (A), where (A1) represents teeth to be treated with application of Nano silver fluoride solution on remaining carious dentin prior to final permanent glass ionomer restoration application, (A2) represents comparator group to be restored without Nano silver fluoride application prior to restoration. Every participant will receive both the intervention and control treatment. Image of radiographic density of remaining carious dentin will be evaluated using PSP plate at baseline immediately after restoration and after 6 months after restorative procedures.
The null hypothesis tested is that application of Nano silver fluoride solution prior to glass ionomer restoration will not increase radiopacity of the underlying dentin treated by incomplete carious removal technique compared to that of direct glass ionomer restoration without prior application of Nano silver fluoride.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| nano silver fluoride solution | Experimental | carious dentin to be treated with partial caries excavation with application of nano silver fluoride solution prior to glass ionomer restoration. |
|
| no nano silver fluoride | No Intervention | carious dentin to be treated with partial caries excavation without application of nano silver fluoride solution restored directly with glass ionomer. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| nano silver fluoride solution | Other | prepared Nano-silver fluoride could have the capability to arrest caries. As its Nano silver particles have an antimicrobial activity against Mutans Streptococci and Lactobacilli; the main pathogens involved in the development of carious lesions. In addition, its fluoride component is well known to enhance remineralization and inhibit bacterial activity. So, Nano silver fluoride could be a promising solution to combat residual bacteria in tooth cavity with effective remineralization potential on remaining carious dentin |
| Measure | Description | Time Frame |
|---|---|---|
| Caries remineralization. (Mineral density) | using Density measurement tool in the Digora software | six months |
| Measure | Description | Time Frame |
|---|---|---|
| dentin bridge formation. | Linear measurement tool in the Digora software in Mm | six months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Heba Ah El deeb | Associate professor, Conservative dentistry department Cairo University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rahma Ahmed | Giza | 002 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24930870 | Background | Santos VE Jr, Vasconcelos Filho A, Targino AG, Flores MA, Galembeck A, Caldas AF Jr, Rosenblatt A. A new "silver-bullet" to treat caries in children--nano silver fluoride: a randomised clinical trial. J Dent. 2014 Aug;42(8):945-51. doi: 10.1016/j.jdent.2014.05.017. Epub 2014 Jun 12. |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Jun 6, 2020 | |
| Reset | Jun 25, 2020 | |
| Release | Jul 18, 2020 |
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split mouth randomized clinical trial
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| Reset | Aug 3, 2020 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Jun 6, 2020 | Jun 25, 2020 | |||
| Jul 18, 2020 | Aug 3, 2020 |