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Dental caries is one of the most common oral diseases of childhood and is considered as a major public health problem especially in areas with poor access to dental care. In a recent cross sectional study carried out in Egypt on 1000 child aged from 3-6 years, it was found that 61.4% of these children had dental caries. In order to avoid serious complications of untreated dental caries such as pain, infections, emergency visits and possibly hospitalization , an effective low cost treatment should be identified particularly in areas with poor dental access.
Studies have proven that silver diamine fluoride (SDF) is a topical fluoride that has the ability to effectively arrest and prevent dental caries.
It was concluded that fluoride uptake into dentine from conventional GI restorations was not affected in the presence of SDF and KI. It was also mentioned that the results may be different if conditioning is applied not etching and recommended this for future investigation.
Aim: Therefore, the aim of this study is to determine whether carious primary molars treated with SDF and Potassium iodide (KI) prior to placing resin modified glass ionomer (RMGI) restorations will affect the fluoride uptake into primary dentine or not.
Study Setting:
Freshly extracted discarded primary molars were collected from outpatient clinic of Pediatric Dentistry Department, Faculty of Dentistry, Cairo University at the end of every day.
Control Group: One half empty and the other half with Resin Modified Glass Ionmer (RMGI) only.
Intervention Group : One half empty and the other half SDF+KI+RMGI
Data showed parametric distribution so; it was represented by mean and standard deviation (SD) values. Independent and paired t-tests were used for inter and intragroup comparisons respectively. The significance level was set at p ≤0.05 within all tests. Statistical analysis was performed with R statistical analysis software version 4.0.3 for windows (R Core Team, 2020).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control Group (A) : RMGI restoration without SDF and KI. | No Intervention | • RMGI restoration without SDF and KI. | |
| Intervention Group (B): Pretreatment with SDF and KI prior to RMGI restoration. | Experimental | • Pretreatment with SDF and KI prior to RMGI restoration. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Silver diamine fluoride | Drug | a layer of 38% SDF solution was topically applied to the cavity using a micro brush, immediately followed by a saturated Potassium Iodide KI solution using a micro brush also, then a creamy white precipitate was immediately formed, KI was applied until the white precipitate turned clear. |
| Measure | Description | Time Frame |
|---|---|---|
| Fluoride uptake into dentine | Fluoride weight percent in dentin under Resin Modified Glass Ionomer Restoration in primary molars | 2 weeks |
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Inclusion Criteria:
• Carious primary extracted molars.
Exclusion Criteria:
• Presence of restorations.
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| Name | Affiliation | Role |
|---|---|---|
| Rania Nasr, Assoc. Prof. | Faculty of Dentistry, Cairo University, Egypt | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Pediatric Dentistry, Faculty of Dentistry, Cairo University | Cairo | 0022 | Egypt | |||
| Faculty of Dentistry, Cairo University |
Protocol and Abstract
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Extracted Discarded Primary Molars divided into CONTROL Group & INTERVENTIONAL Group
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The principle investigator & co-investigator are masked before assessing the outcomes
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|
| Cairo |
| 0022 |
| Egypt |
| ID | Term |
|---|---|
| D003731 | Dental Caries |
| ID | Term |
|---|---|
| D017001 | Tooth Demineralization |
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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| ID | Term |
|---|---|
| C024633 | silver diamine fluoride |
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