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N-Acetylcysteine and L-carnitine were used in pcos patients
N-Acetylcysteine was compared to L-carnitine in clomiphene citrate in Pcos women to detect the hormonal and metabolic effect
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| N-Acetylcysteine | Experimental | N-Acetylcysteine used by clomiphene resistant pcos women |
|
| L-carnitine | Active Comparator | L-carnitine used by clomiphene resistant pcos women |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| N-Acetylcysteine | Drug | N-Acetylcysteine in clomiphene resistant pcos women |
| |
| Measure | Description | Time Frame |
|---|---|---|
| pregnancy rate | number of women with clinical pregnancy | 3 momths |
| Measure | Description | Time Frame |
|---|---|---|
| ovulation rate | number of women with follicle >18mm. | 3 momths |
| abortion rate | number of women with abortions | 3 momths |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| ibrahim A EL sharkwy, MD | FACULTY OF MEDICINE ,ZAGAZIG UNIVERSITY | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Zagazig University | Zagazig | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31273783 | Derived | El Sharkwy IA, Abd El Aziz WM. Randomized controlled trial of N-acetylcysteine versus l-carnitine among women with clomiphene-citrate-resistant polycystic ovary syndrome. Int J Gynaecol Obstet. 2019 Oct;147(1):59-64. doi: 10.1002/ijgo.12902. Epub 2019 Jul 17. |
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the collected data willbe available within 6 months
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| ID | Term |
|---|---|
| D000111 | Acetylcysteine |
| D002331 | Carnitine |
| ID | Term |
|---|---|
| D003545 | Cysteine |
| D000603 | Amino Acids, Sulfur |
| D013457 | Sulfur Compounds |
| D009930 | Organic Chemicals |
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| L-carnitine |
| Drug |
L-carnitine in clomiphene resistant pcos women |
|
|
| D000596 |
| Amino Acids |
| D000602 | Amino Acids, Peptides, and Proteins |
| D050337 | Trimethyl Ammonium Compounds |
| D000644 | Quaternary Ammonium Compounds |
| D000588 | Amines |