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To determine if MRI can detect preoperative invasion of cartilage by laryngeal and hypopharyngeal carcinoma, and to compare it to CT imaging and histopathology in excised larynges and/or hypopharynges.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pharyngo laryngeal MRI | Patient with a laryngeal or hypopharyngeal cancer at any stage, with a doubt about cartilage invasion and eligible for surgical treatment for which there is an indication for performing an MRI in addition to CT at the discretion of the investigator |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pharyngo laryngeal MRI | Other | Patients will be outgoing a pharyngolaryngeal MRI, with injection of gadolinium, in addition to the CT imaging. They will have this MRI in case of doubt about cartilage invasion. It will be realised during the time between the CT imaging and the day of surgery. Device : gadolinium-based MRI contrast agent This will be realized according to the standard procedure. |
| Measure | Description | Time Frame |
|---|---|---|
| Endoscopy | Tumor stage and cartilage invasion as determined by endoscopy : invaded/non invaded/undetermined | 1-4 weeks |
| CT scan | Tumor stage and cartilage invasion as determined by CT scan : invaded/non invaded/undetermined | 1-4 weeks |
| MRI | Tumor stage and cartilage invasion as determined by MRI : invaded/non invaded/undetermined | 1-4 weeks |
| Anatomopathological analysis | Tumor stage and cartilage invasion as determined by histopathology in excised pieces : invaded/non invaded/undetermined | 2-4 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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Patient with a laryngeal or hypopharyngeal cancer at any stage, with a doubt about cartilage invasion and eligible for surgical treatment.
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| Name | Affiliation | Role |
|---|---|---|
| Philippe CERUSE, Pr | Service ORL et chirurgie cervico-faciale, Hôpital de la Croix rousse | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Service ORL et chirurgie cervico-faciale, Hôpital de la Croix rousse | Lyon | 69004 | France |
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| ID | Term |
|---|---|
| D007012 | Hypopharyngeal Neoplasms |
| D007822 | Laryngeal Neoplasms |
| ID | Term |
|---|---|
| D010610 | Pharyngeal Neoplasms |
| D010039 | Otorhinolaryngologic Neoplasms |
| D006258 | Head and Neck Neoplasms |
| D009371 | Neoplasms by Site |
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|
| D009369 | Neoplasms |
| D010608 | Pharyngeal Diseases |
| D009057 | Stomatognathic Diseases |
| D010038 | Otorhinolaryngologic Diseases |
| D007818 | Laryngeal Diseases |
| D012140 | Respiratory Tract Diseases |
| D012142 | Respiratory Tract Neoplasms |