Nocturnal Hypertension and Non-Dipping Blood Pressure

Mechanisms of Nocturnal Hypertension and Non-Dipping Blood Pressure Patterns

The purpose of this study is to determine if high salt diet contributes to high nighttime blood pressure. The investigators will determine if high compared to low salt diet increases 24-hour blood pressure levels. The investigators will also determine if high salt diet affects blood vessel stiffness, cardiac output, and sleep apnea. The study will also determine how high salt diet affects the activity of certain genes related to control of blood pressure. A total of 60 participants will be enrolled in the study.

Inclusion Criteria:

• Nocturnal hypertension

Exclusion Criteria:

• Stage 2 clinic hypertension
• History of congestive heart failure
• Chronic kidney disease,
• Diabetes with insulin use
• History of a cardiovascular event
• Pregnant or nursing
• Current use of continuous positive airway pressure
• Shift work
• A known circadian rhythm disorder