CLA and Vitamin D on Protein Turnover

Randomized Controlled Trial to Evaluate the Independent and Combined Effects of Conjugated Linoleic Acids and Vitamin D on Muscle Protein Turnover in Older Adults

To conduct a randomized, double-blind, controlled clinical trial to determine the independent and combined effects of dietary conjugated linoleic acid (CLA) and vitamin D supplementation on anabolic signaling, the expression of growth regulatory factors, and muscle protein turnover in older adults.

Inclusion Criteria:

• BMI >/= 18.5 and </= 35.0
• Serum 25OH-VitD3 < 35 ng/ml

Exclusion Criteria:

• Diabetes
• COPD