Conjugated Linoleic Acid (1:1 Isomer Mixture) Intake in Overweight People

Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Tonalin(R)Intake in Overweight People

The aim of the study was to examine the effects and safety of 3 g of a 1:1 mix of c9-t11 and t10-c12 (Tonalin®) on weight control and body composition in healthy overweight individuals who maintained their normal dietary and exercise patterns.

Inclusion Criteria:

• aged 30-55 years
• grade II overweight (BMI≥27 but <30 kg/m2)
• not to be adhered to any calorie restriction diet
• not to be taking any weight control medication or have lost more than 5 kg in the three months prior to the study

Exclusion Criteria:

• suffering of serious concomitant disease such as diabetes mellitus type II, metabolic syndrome (according to the criteria of the Adult Treatment Panel III), cancer, kidney disease, HIV, tuberculosis, cardiovascular disease, chronic obstructive pulmonary disease, eating disorders.
• having undergone bariatric surgery and/or intestinal resection
• breastfeeding and pregnancy.
• not to give their signed, informed consent to be included in the study.