Serum Biomarkers in Diagnosis and Predicting Prognosis of Ovarian Cancers

Value of TFF3, SFRP4, Romo1 and NFKB as Serum Biomarkers in Diagnosis and Predicting Prognosis of Ovarian Cancers

This study evaluates the usefulness of serum levels of trefoil factor 3 (TFF3), secreted frizzled related protein 4 (sFRP-4), reactive oxygen species modulator 1 (Romo1) and nuclear factor (NF)-κB as potential diagnostic and prognostic biomarkers in ovarian carcinoma.

Inclusion Criteria:

• Primary diagnosis of epithelial ovarian carcinoma.

Exclusion Criteria:

• Patients with recurrence.
• Patients who received neoadjuvant chemotherapy or radiotherapy
• Presence of any secondary malignancy