Effect of Concurrent Hookah and Alcohol Consumption on Smoking Topography and Toxicant Exposure
Effect of Concurrent Hookah and Alcohol Consumption on Smoking Topography and Toxicant Exposure
The purpose of the current study is to investigate in a prospective randomized cross-over trial, the impact of alcohol versus a placebo drink on smoking behavior and topography (duration and frequency of puffing), abuse liability, and toxicity. It is hypothesized that drinking alcohol before smoking will be associated with longer puffs and shorter duration between puffs and greater abuse liability and toxicity.
Inclusion Criteria:
Report using hookah at least 1 time per month over the past 6 months
Are at least 21 years old
Speak and understand English
Do not currently suffer from lung disease including asthma, CF, or COPD
Do not currently suffer from heart disease
Are not currently pregnant or breast-feeding or have plans to become pregnant or begin breast-feeding at any point during the study
No current, regular use of >5 cigarettes or other tobacco products (e.g., e-cig, cigar, etc.) per month.
No current marijuana use > 5 times per month
No use of illicit drugs during the past 30 days
willing to provide informed consent and abstain from all tobacco, nicotine, and marijuana use for at least 12 hours and abstain from alcohol for at least 24 hours prior to each of the two sessions
Live within 25 miles of the study location.
Have a friend who is eligible and willing to participate.
Consume 2 or more or one or more drinks per episode for men and women, respectively
Drink alcohol at least one time per week
Not currently be seeking treatment for alcohol use
Able to answer at least two hookah-specific screening questions from the screener.
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Exclusion Criteria: