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| Name | Class |
|---|---|
| Comisión Nacional de Investigación CientÃfica y Tecnológica | OTHER_GOV |
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The present study will investigate the effects of a mindfulness training on emotion regulation and social cognition, using several psychological, behavioral, psychophysiological and neuroimaging methods.
The aim of the present study is to evaluate the impact of a mindfulness intervention, particularly the mindfulness-based stress reduction (MBSR), on the capacities of emotion regulation and social cognition, in caring/helping professions which are vulnerable to stress. In the context of a longitudinal intervention study, a randomized controlled trial, the efficacy of the MBSR to increase the capacity for self-emotion regulation, empathic attunement, and compassion capacities will be measured. For doing this, several psychological, behavioral, psychophysiological and neuroimaging brain measurements will be used.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Mindfulness group | Experimental | Mindfulness based stress reduction: 8 week program, including meditation, body-awareness, and yoga practices. Daily assignments and home practices during 50 minutes per day. |
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| Reading group | Active Comparator | Reading and sharing group: 8 week program, including readings, interpersonal exchanges, group discussion, listening and role playing exercises. Daily assignments and home practices during 50 minutes per day. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Mindfulness group | Behavioral | 8 week program |
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| Measure | Description | Time Frame |
|---|---|---|
| Activation changes in emotions related brain regions. Measured by significant changes in the BOLD (blood oxygenated level dependent) signal from task based functional magnetic resonance imaging. | first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention. | |
| Changes in resting state functional connectivity within brain networks. Measured by significant changes in intrinsic functional connectivity parameters, estimated from the resting state BOLD signal, during functional magnetic resonance imaging. | first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention. |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in resting state functional connectivity between inter-networks connectivity. | Changes between brain networks connectivity (including DMN, fronto-parietal and salience networks), measured as significant changes in inter-networks connectivity parameters estimated from the temporal correlation of intrinsic functional connectivity networks. | first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Isabel Dziobek, Professor, PhD. | Contact | (030) 2093-6186 | isabel.dziobek@hu-berlin.de | |
| Simon Guendelman, MD. | Contact | (030) 2093-6186 | simon.guendelman@hu-berlin.de |
| Name | Affiliation | Role |
|---|---|---|
| Isabel Dziobek, Professor, PhD. | Humboldt Universität. | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Berlin School of Mind & Brain, Humboldt Universität. | Recruiting | Berlin | State of Berlin | 10117 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35259523 | Derived | Guendelman S, Bayer M, Prehn K, Dziobek I. Towards a mechanistic understanding of mindfulness-based stress reduction (MBSR) using an RCT neuroimaging approach: Effects on regulating own stress in social and non-social situations. Neuroimage. 2022 Jul 1;254:119059. doi: 10.1016/j.neuroimage.2022.119059. Epub 2022 Mar 5. |
| Label | URL |
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| Related Info | View source |
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| ID | Term |
|---|---|
| D013315 | Stress, Psychological |
| ID | Term |
|---|---|
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D000099024 | Mindfulness-Based Stress Reduction |
| ID | Term |
|---|---|
| D064866 | Mindfulness |
| D015928 | Cognitive Behavioral Therapy |
| D001521 | Behavior Therapy |
| D011613 | Psychotherapy |
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| Reading group | Behavioral | 8 week program |
|
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| Changes in regional brain morphometry in stress processing related areas. Measured by significant changes in regional grey matter density estimated from structural magnetic resonance imaging. | first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention. |
| Behavioural tasks: mind-wandering task | Changes in mind-wandering task, measured as changes in task-unrelated thoughts. | first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention. |
| Changes in personality functioning. | Significant changes in levels of personality functioning measured by the operationalized psychodynamic diagnosis scale. | first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention. |
| Experience Sampling of emotional tolerance | Significant changes in self-reported capacity for emotion tolerance. | first acquisition period during 3 weeks before the intervention, last acquisition period during 3 weeks after the intervention. And during the intervention period everyday. |
| Changes in psychophysiological measurements of stress (sympathetic component) | Activation changes in psychophysiological stress parameters using Skin Conductance Response (measured as significant changes in tonic and phasic response levels) during an emotion regulation task. | first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention. |
| Changes in psychophysiological measurements of stress (vagal component) | Activation changes in psychophysiological stress parameters using Heart Rate Variability (power analysis of high frequency sub-bands of heart rate spectrum), during an emotion regulation task. | first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention. |
| Behavioural tasks: empathy test. | Changes in empathy test, measured as changes in levels of cognitive and affective empathy. | first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention. |
| Changes in self-reported affective states | Significant changes in self-reported levels of negative and positive affects measured by the PANAS scale. | first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention. |
| Changes in social functioning | Significant changes in the interpersonal competence questionnaire self-reported scale. | first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention. |
| D004191 |
| Behavioral Disciplines and Activities |