Diagnosis of Bladder Pain Syndrome / Interstitial Cystitis

Diagnosis of Bladder Pain Syndrome / Interstitial Cystitis

To identify new, simple and reliable biomarkers for bladder pain syndrome/interstitial cystitis (BPS/IC) for diagnosis of this disease.

Collection and analyses of bladder biopsies, bladder washings, blood and urine samples of patients with bladder pain syndrome/interstitial cystitis (BPS/IC), overactive bladder syndrome (OAB) and bladder-healthy controls. Analyses include ELISA, RT-qPCR, DNA sequencing, and immunohistochemistry techniques. Differences between patient groups are statistically evaluated.

Inclusion Criteria:

• patient with diagnosed BPS/IC, OAB or healthy controls
• included healthy controls must have another pelvic surgery planned (e.g. hysterectomy)
• being able to act and judge

Exclusion Criteria:

• unstable endocrinological situation
• severe illness