Supervised Exercise-training in Children With Insulin Resistance or Healthy Metabolic Profile

Supervised Exercise-training in Children With Insulin Resistance or Healthy Metabolic Profile: Cardiometabolic Risk Factors and Muscular Strength Changes in Responders and Non Responders

Despite exercise training decrease blood fasting glycemia in 'average' terms, there is a wide interindividual variability after exercise training explored mainly in adults but not in children. Thus, is yet unknown what baseline health status as well as the influence of what health variable may produce more/less non-responder (NR) prevalence (i.e., percentage of subjects who experienced a non-change/worsened response after training in some metabolic outcomes) after exercise training in school children.

Inclusion Criteria:

• Diagnosed of insulin resistance by one of three plasmatic glucose control: HOMA-IR ≥3.0,
• Fasting insulin levels ≥15 µUI/dL or fasting glucose ≥100 and ≤126 mg/dL within the enrolment stage applied at school (i.e., ≤3 months),
• Physical inactivity (volume of ≤60 min/day of moderate physical activity),
• To be participating of regular practical physical education classes at school (i.e., 90 min/week),
• Living only in urban areas.

Exclusion Criteria:

• Potential medical, musculoskeletal problems or a familial history of T2DM,
• Ischemic disease,
• Arrhythmia,
• Asthma,
• Utilization of drugs that modulate the metabolic and respiratory control.