Neurodevelopment Outcomes After Pediatric Dental Caries Treatment Under General Anaesthesia

Neurodevelopment Outcomes After Pediatric Dental Caries Treatment Under General Anaesthesia

The purpose of this study is to investigate whether early expose to general anaesthesia will influence neurodevelopment.

Participants, according to the state of illness and clinical requirements, assigned to receive dental caries treatment with or without general anesthesia. During the follow-up, various of neurodevelopment assessment will be done at specific timepoint to investigate whether general anaesthesia will influence neurodevelopment.

Inclusion Criteria:

• Gestational age>=36 weeks
• American Society of Anesthesiologists（ASA） physical status Ⅰ or Ⅱ，with very limited systemic disease.
• Age<=6 yr

Exclusion Criteria:

• did not provide research authorization；
• unable to contact or inconvenient for follow-up;
• hypersensitive to general anesthesia drug;
• previous exposure to general anesthesia in utero;
• previous exposure to general anesthesia as a neonate
• previous exposure to psychotropic medication;
• complications at birth such as low weigh, hypoxia, or cerebral edema;
• any other known diseases may influence the neurodevelopment