Comparison of ER:YAG Laser, CO2 Laser and Scalpel Excision of Fibrous Hyperplasia on the Buccal Mucosa

Clinical and Histopathological Comparison of ER:YAG Laser, CO2 Laser and Scalpel Excision of Fibrous Hyperplasia on the Buccal Mucosa

The aim of the RCT is to analyse clinical and histopathological particularities for excisional biopsies of fibrous hyperplasia in the buccal mucosa performed with Er:YAG laser, CO2 laser and scalpel. The primary outcome parameter is to evaluate the thermal damage zone on the excised specimens. Secondary parameters are time of surgery, intraoperative bleeding, the need for additional electrocoagulation or sutures and patient's postsurgical perception of pain, other postsurgical effects and use of analgesics.

Inclusion Criteria:

• Clinical tentative diagnosis of fibrous hyperplasia in the buccal mucosa
• Fibrous hyperplasia dimensions 0.5 to 2 cm
• Patient understands and reads the German language
• Written informed consent

Exclusion Criteria:

• Untreated diabetes Typ II
• Severe infectious disease (HIV, hepatitis)
• Severe psychiatric disease
• Immunosuppressive therapy
• Anticoagulation
• Pregnancy; a pregnancy test (Clearblue®) is performed in women of childbearing age