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The vagal stimulation is a promising therapy for a lot of disorders as well as hemodynamic regulatory way. In order to minimize the harm of a surgery chip implantation, actually it was developing a non-invasive device that is able to stimulate the auricular branch of vagal nerve. It has been shown that trans-auricular vagal stimulation (tVNS) causes direct stimulation of the vagal nerve. However, there are still no strong evidences about it actions regarding the autonomic modulation. The aim of this study is to evaluate effects of tVNS on heart rate, blood pressure and the autonomic control in healthy and hypertensive subjects, at rest and after orthostatic position
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Healthy Subjects | Experimental | transcutaneous vagal nerve stimulation |
|
| Hypertensive Subjects | Experimental | transcutaneous vagal nerve stimulation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| transcutaneous vagal nerve stimulation on | Device | electrical current on positioned in the ear to estimate vagal branch of auricular nerve |
|
| Measure | Description | Time Frame |
|---|---|---|
| Autonomic control response to transcutaneous vagal nerve stimulation | sympathetic and parasympathetic response to non-invasive vagal nerve stimulation | 40 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Blood pressure changes to transcutaneous vagal nerve stimulation | systemic response to non-invasive vagal nerve stimulation | 40 minutes |
| Heart Rate changes to transcutaneous vagal nerve stimulation |
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Normotensive group Inclusion Criteria:
Normotensive group Exclusion Criteria:
Hypertensive group Inclusion Criteria:
Hypertensive group Exclusion Criteria:
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| transcutaneous vagal nerve stimulation off | Device | an electrical current off positioned in the ear to estimate vagal branch of auricular nerve |
|
cardiac response to non-invasive vagal nerve stimulation
| 40 minutes |