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| ID | Type | Description | Link |
|---|---|---|---|
| F32MH108311 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute of Mental Health (NIMH) | NIH |
| The Hilda & Preston Davis Foundation | OTHER |
The purpose of this study is to investigate areas of the brain responsible for self-regulation in adult women who have never had an eating disorder with women who have bulimia nervosa. More specifically, investigators are interested in changes in brain activation (e.g., changes in blood flow and oxygen use) when inhibiting responses and regulating emotions. Data collection will rely on a technology called functional magnetic resonance imaging (fMRI).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Women with Bulimia Nervosa | |||
| Women Healthy Controls |
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| Measure | Description | Time Frame |
|---|---|---|
| Self-Regulatory Control | Functional Magnetic Resonance Imaging will be used to assess brain activation associated with motor inhibitory control and affect regulation in women with bulimia nervosa (BN) | Day 2 (fMRI Scan) |
| Measure | Description | Time Frame |
|---|---|---|
| Goal-Directed Action Control | An computerized instrumental learning task will be used to assess performance of women with and without bulimia nervosa. | Day 1 |
| Eating Disorder Relevance | The Eating Disorder Examination (EDE) will be conducted to assess relative associations of motor, affective, and goal-directed action control with bulimia nervosa severity. |
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General Inclusion Criteria:
Female
Right-handed
Between the ages of 18 and 35 years
*For Women with Bulimia Nervosa:
Binge eating (i.e., eating a large amount of food while experiencing a sense of loss of control)
Purging via self-induced vomiting (other methods may also be endorsed)
General Exclusion Criteria:
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Women (ages 18-35 years) with bulimia nervosa, and age- and BMI-matched healthy controls.
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| Name | Affiliation | Role |
|---|---|---|
| Laura A. Berner, Ph.D. | University of California, San Diego | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UCSD Eating Disorders Center for Treatment and Research | San Diego | California | 92121 | United States |
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| ID | Term |
|---|---|
| D052018 | Bulimia Nervosa |
| D002032 | Bulimia |
| D000080103 | Emotional Regulation |
| ID | Term |
|---|---|
| D001068 | Feeding and Eating Disorders |
| D001523 | Mental Disorders |
| D006963 | Hyperphagia |
| D012817 | Signs and Symptoms, Digestive |
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| Day 0 |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D000068356 | Self-Control |
| D012919 | Social Behavior |
| D001519 | Behavior |