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difficulty in recruiting
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Women in assisted reproduction treatment they receive own or donated embryos and presenting an endometrial development less than 5 mm despite having received treatment with estrogen therapy knowing the clinical value of using the PRGF-Endoret therapy and endometrial level applications to improve endometrial thickness endometrial preparations for embryo transfer.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Endometrium with less than 5mm | Experimental | Women receiving cycle of oocytes outside or embryos (own / others), in the treatment of substituted cycle type. Less than 5mm despite 10 days with standard doses of estrogen |
|
| Endometrium with more than 5mm | No Intervention | Women receiving cycle of oocytes outside or embryos (own / others), in the treatment of substituted cycle type. More than 5mm despite 10 days with standard doses of estrogen |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Growth Factor, Platelet-Derived | Drug | 0,5 mL, vaginal use , 3 dose number |
|
| Measure | Description | Time Frame |
|---|---|---|
| To evaluate the growth of endometrial thickness | The endometrial thickness will be measured by vaginal ultrasound. Endometrium less than 5 mm will be treated | During ovarian stimulation protocol 8-12 days |
| Measure | Description | Time Frame |
|---|---|---|
| Analyze the impact of using platelet plasma on rates of implantation and pregnancy. | The biochemical determination of the hormone ßhcg will be performed 12 days after embryo transfer | During ovarian stimulation protocol 8-12 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| IVI Bilbao | Leioa | Vizcaya | 48940 | Spain |
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| ID | Term |
|---|---|
| D010982 | Platelet-Derived Growth Factor |
| ID | Term |
|---|---|
| D036341 | Intercellular Signaling Peptides and Proteins |
| D010455 | Peptides |
| D000602 | Amino Acids, Peptides, and Proteins |
| D001798 | Blood Proteins |
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| D011506 | Proteins |
| D001685 | Biological Factors |