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The aim of the study is to evaluate the effect of the consumption of a food supplement (live saccharomyces cerevisiae) on lipidic profile in moderate hypercholesterolemic subjects.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Live Saccharomyces cerevisiae | Active Comparator | Live Saccharomyces cerevisiae. 2 capsules per day (1 g). |
|
| Yeast cell wall | Active Comparator | Yeast cell wall. 2 capsules a day (700 mg). |
|
| Placebo | Placebo Comparator | Maize starch and magnesium stearate. 2 capsules a day. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Saccharomyces cerevisiae | Dietary Supplement | Live Saccharomyces cerevisiae |
|
| Measure | Description | Time Frame |
|---|---|---|
| Plasma LDL cholesterol | 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| LDL cholesterol | 4 weeks | |
| Total cholesterol | 4 weeks, 8 weeks | |
| Triglycerides |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institut Pasteur de Lille | Lille | 59000 | France |
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| ID | Term |
|---|---|
| D050171 | Dyslipidemias |
| ID | Term |
|---|---|
| D052439 | Lipid Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| Lynside Wall Basic | Dietary Supplement | yeast cell walls |
|
| Placebo | Dietary Supplement | Maize starch and magnesium stearate |
|
| 4 weeks, 8 weeks |
| HDL cholesterol | 4 weeks, 8 weeks |
| Apo B | 4 weeks, 8 weeks |
| Apo A1 | 4 weeks, 8 weeks |
| gamma GT | 4 weeks, 8 weeks |
| ASAT | 4 weeks, 8 weeks |
| ALAT | 4 weeks, 8 weeks |