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| Name | Class |
|---|---|
| Heidelberg University, Psychotherapy Research Department | UNKNOWN |
| Heidelberg University, Clinic for Child and Youth Psychiatry | UNKNOWN |
| Johannes Gutenberg University Mainz | OTHER |
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A feasibility and pilot trial to investigate the feasibility of a newly manualized psychotherapy "Mentalization-Based Training for Adolescents with Conduct Disorder (MBT-CD)"
Background: Conduct Disorder is a severe and complex mental disorder with the highest incidence in adolescence. Previous studies have shown that family-oriented interventions are effective in the treatment of Conduct Disorder. However, most therapies focus rather on symptom management and less on etiological causes without inclusion of the family in the therapeutic process. Previous research has linked specific symptoms of Conduct Disorder with deficits in mentalization ability. Mentalization is the ability to perceive one's own and other's behavior as the product of affective and cognitive mental states. Low or missing mentalization abilities are regarded as a risk factor for the development and chronification of Conduct Disorder.
Aims: The study aims to investigate the feasibility of a newly manualized psychotherapy "Mentalization-Based Training for Adolescents with Conduct Disorder (MBT-CD)" that strives to decrease symptoms associated with Conduct Disorder by increasing mentalization in adolescents and their families.
Methods: The study is feasibility and piolot trial, carried out in Heidelberg (Germany), and Mainz (Germany). Adolescents aged between 11-18, who meet the DSM-5 criteria for Conduct Disorder will receive MBT-CD. Times of measurement: t0 (Screening), T1 (Baseline, at the beginning of therapy), T2 (3 months after the beginning of therapy), T3 (at the end of therapy, after 6 months), T4 (follow-up, after 9 months).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MBT-CD | Experimental | Mentalization-based treatment program |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MBT-CD | Other | MBT-CD is a disorder-specific modification of MBT, initially developed for patients with Borderline Personality Disorder. It is a manualized and psychodynamically oriented psychotherapy with the aim to increase the mentalization capacity of adolescents in close relationships. The therapy consists of 2 psychoeducational group sessions, 30 individual therapy sessions and 10 family sessions. The average duration of therapy is 6 months. |
| Measure | Description | Time Frame |
|---|---|---|
| Structured Clinical Interview for DSM-IV Axis II Disorders (SCID-II) | Change from baseline in SCID-II at 12 months (at the end of therapy) | |
| Subtypes of Antisocial Behaviour Questionnaire (STAB) | Change from baseline in STAB at 6 months | |
| Subtypes of Antisocial Behaviour Questionnaire (STAB) | Change from baseline in STAB at 12 months (at the end of therapy) | |
| Subtypes of Antisocial Behaviour Questionnaire (STAB) | Change from baseline in STAB at 18 months (follow-up) | |
| Reactive-Proactive-Aggression Questionnaire (RPQ) | Change from baseline in RPQ at 6 months | |
| Reactive-Proactive-Aggression Questionnaire (RPQ) | Change from baseline in RPQ at 12 months (at the end of therapy) | |
| Reactive-Proactive-Aggression Questionnaire (RPQ) | Change from baseline in RPQ at 18 months (follow-up) |
| Measure | Description | Time Frame |
|---|---|---|
| Global Assessment of Functioning (GAF) | Change from baseline in GAF at 12 months (at the end of therapy) | |
| Clinical Global Impression (CGI-SI) | Change from baseline in CGI-SI at 12 months (at the end of therapy) |
| Measure | Description | Time Frame |
|---|---|---|
| Working Alliance Inventory (WAI) | Treatment related variable (moderator) | Change from baseline in WAI at 6 months |
| Working Alliance Inventory (WAI) | Treatment related variable (moderator) |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Svenja Taubner, Prof. | Institute for Psychosocial Prevention, Heidelberg University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Heidelberg University | Heidelberg | 69115 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 27548462 | Background | Taubner S, Zimmermann L, Ramberg A, Schroder P. Mentalization Mediates the Relationship between Early Maltreatment and Potential for Violence in Adolescence. Psychopathology. 2016;49(4):236-246. doi: 10.1159/000448053. Epub 2016 Aug 23. | |
| 23200287 | Background | Rossouw TI, Fonagy P. Mentalization-based treatment for self-harm in adolescents: a randomized controlled trial. J Am Acad Child Adolesc Psychiatry. 2012 Dec;51(12):1304-1313.e3. doi: 10.1016/j.jaac.2012.09.018. |
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| ID | Term |
|---|---|
| D019955 | Conduct Disorder |
| ID | Term |
|---|---|
| D019958 | Attention Deficit and Disruptive Behavior Disorders |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
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|
| Levels of Personality Functioning - Questionnaire Adolescence (LoPF-QA) | Change from baseline in LoPF-QA at 12 months (at the end of therapy) |
| Levels of Personality Functioning - Questionnaire Adolescence (LoPF-QA) | Change from baseline in LoPF-QA at 18 months (follow-up) |
| Reflective Functioning Questionnaire (RFQ) | Change from baseline in RFQ at 12 months (at the end of therapy) |
| Reflective Functioning Questionnaire (RFQ) | Change from baseline in RFQ at 18 months (follow-up) |
| Movie for the Assessment of Social Cognition (MASC) | Change from baseline in MASC at 12 months (at the end of therapy) |
| 10 round Trust Game Task (TGT) | Change from baseline in TGT at 12 months (at the end of therapy) |
| Social Hierarchy Task (SHT) | Change from baseline in SHT at 12 months (at the end of therapy) |
| Approach-Avoidance Task (AAT) | Change from baseline in AAT at 12 months (at the end of therapy) |
| Symptom Checklist-90-Revised (SCL-90R) | Change from baseline in SCL-90R at 12 months (at the end of therapy) |
| Stress Index for Parents of Adolescents (SIPA) | Change from baseline in SIPA at 12 months (at the end of therapy) |
| Stress Index for Parents of Adolescents (SIPA) | Change from baseline in SIPA at 18 months (follow-up) |
| drop-out rates | after 12 months (at the end of therapy) |
| cost-effectiveness | Cost-effectiveness will be measured by participation in training/school, rehospitalization, internment | after 12 months (at the end of therapy) |
| Change from baseline in WAI at 12 months (at the end of therapy) |
| Experiences in Close Relationships - Revised (ECR-R) | Treatment related variable (moderator) | Change from baseline in ECR-R at 12 months (at the end of therapy) |
| Emotion Regulation Questionnaire (ERQ) | Treatment related variable (moderator) | Change from baseline in ERQ at 12 months (at the end of therapy) |
| Emotion Regulation Questionnaire (ERQ) | Treatment related variable (moderator) | Change from baseline in ERQ at 18 months (follow-up) |
| Zurich Brief Questionnaire for the Assessment of Parental Behaviors (ZKE) | Treatment related variable (moderator) | Change from baseline in ZKE at 12 months (at the end of therapy) |
| The Mini-International Neuropsychiatric Interview (MINI) | Treatment related variable (moderator) | Change from baseline in MINI at 12 months (at the end of therapy) |
| Youth Psychopathy Traits Inventory (YPI) | Treatment related variable (moderator) | only baseline assessment |
| Cultural-Fair-Test (CFT-2) | Treatment related variable (moderator) | only baseline assessment |
| Childhood Experience of Care and Abuse Questionnaire (CECA-Q) | Treatment related variable (moderator) | only baseline assessment |
| Dimensional Assessment of Personality Pathology - Basic Questionnaire (DAPP-BQ) | Treatment related variable (moderator) | only baseline assessment |
| 23512713 | Background | Taubner S, White LO, Zimmermann J, Fonagy P, Nolte T. Attachment-related mentalization moderates the relationship between psychopathic traits and proactive aggression in adolescence. J Abnorm Child Psychol. 2013 Aug;41(6):929-38. doi: 10.1007/s10802-013-9736-x. |
| Background | McGauley G, Yakeley J, Williams W, Bateman AW. Attachment, mentalization and antisocial personality disorder. The possible contribution of mentalization-based treatment. European Journal of Psychotherapy & Counselling. 2011; 13 (4): 371-393; doi: 10.1080/13642537.2011.629118. |
| 36434148 | Derived | Hauschild S, Kasper L, Volkert J, Sobanski E, Taubner S. Mentalization-based treatment for adolescents with conduct disorder (MBT-CD): a feasibility study. Eur Child Adolesc Psychiatry. 2023 Dec;32(12):2611-2622. doi: 10.1007/s00787-022-02113-4. Epub 2022 Nov 25. |
| 34215323 | Derived | Taubner S, Hauschild S, Kasper L, Kaess M, Sobanski E, Gablonski TC, Schroder-Pfeifer P, Volkert J. Mentalization-based treatment for adolescents with conduct disorder (MBT-CD): protocol of a feasibility and pilot study. Pilot Feasibility Stud. 2021 Jul 2;7(1):139. doi: 10.1186/s40814-021-00876-2. |