Effect of Magnesium Supplementation for Children With Drug Resistant Idiopathic Epilepsy

Magnesium Supplementation for Children With Drug Resistant Idiopathic Epilepsy: A Pilot Study

Effect of oral magnesium sulfate (Mg) supplementation will be studied. Children with drug resistant idiopathic epilepsy following up in Pediatric Neurology Clinic, Ain Shams University, will be randomized to either Mg add-on treatment group or anti-epileptic drugs AEDs alone. Serum magnesium, seizure control and Intelligent quotation (IQ) will be done at base line and after 6 months of treatment.

The Aim of this work was to study the effect of Magnesium as add on therapy on clinical seizure control in drug resistant idiopathic epilepsy and IQ.

Inclusion Criteria:

• Children with drug resistant idiopathic epilepsy

Exclusion Criteria:

• Structural, Metabolic, Infectious and Unknown etiology epilepsy
• Any neurological disease other than epilepsy
• Any nutritional disorder
• Any other systemic diseases (including Renal disease, Cardiac arrhythmia)
• Drug intake other than antiepileptic drugs (AED)