Comparison of Different Concentrations of Carbamide as Moisturizers in Ichthyosis Vulgaris

Double Blinded Randomized Clinical Study of Carbamide as Moisturizer in Ichthyosis Vulgaris

A randomized double blinded clinical trial will be conducted comparing the effect of two simple basic moisturizers only different in the concentration of carbamide (urea). The concentrations of carbamide will be tested are 0 and 7.5, respectively. The study will be conducted as a split-body-study and will contain two arms randomized to comparing 0 and 7.5 % carbamide, respectively. Approximately 20 patients with at least clinically verified Ichthyosis Vulgaris will be enrolled to each study arm. The effect of the moisturizers will be assessed by clinical examination (score), patients assesment of effect and measurement of transepidermal water loss (TEWL) and other skin parameters.

Inclusion Criteria:

• Clinically diagnosed with Ichthyosis Vulgaris

Exclusion Criteria:

• All other forms of Ichthyosis