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The investigators prospectively want to compare 3 clinical tests for measuring blood troponin levels in patients presenting to the emergency room with thoracic pain probably related to a myocardial infarction with regard to the time necessary to obtain the test results.
The tests are one laboratory based test and two point of care tests.
Thoracic pain can be caused by a myocardial infarction. The diagnosis of a myocardial infarction can be made by an ECG (ST-elevation myocardial infarction, STEMI). However, some myocardial infarctions can also occur without ST-elevations on the ECG (non-ST-elevation myocardial infarction, non-STEMI). In the latter case, a quick acquisition of blood troponin levels is necessary to coin the diagnosis and initiate treatment. Therefore, the investigators prospectively want to compare 3 clinical tests for measuring blood troponin levels in patients presenting to the emergency room with thoracic pain probably related to a non-STEMI with regard to the time necessary to obtain the test results.
The 3 tests are:
The measured timeframe is the time between venipuncture to the point the test results are known.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Thoracic pain | Patients presenting to the emergency room with thoracic pain probably due to a non-STEMI |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Laboratory based troponin test | Device | acquisition of blood troponin level by Roche Cobas E 603 |
|
| Measure | Description | Time Frame |
|---|---|---|
| time delay until troponin test results are known | From the time of venipuncture to the time the troponin test results are known: up to 6 hours |
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Inclusion Criteria:
Exclusion Criteria:
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Patients presenting to the emergency room with thoracic pain due to a non-STEMI
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| Name | Affiliation | Role |
|---|---|---|
| Pascal Vanelderen, MD, PhDD | Member of Staff | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ziekenhuis Oost-Limburg | Genk | Limburg | 3600 | Belgium |
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| Point of care based troponin test 1 | Device | acquisition of blood troponin level by Radiometer EQT 90 Flex |
|
| Point of care based troponin test 2 | Device | acquisition of blood troponin level by Philips Minicare I-20 |
|
| ID | Term |
|---|---|
| D000072658 | Non-ST Elevated Myocardial Infarction |
| D000787 | Angina Pectoris |
| D060050 | Angina, Stable |
| D000789 | Angina, Unstable |
| D000788 | Angina Pectoris, Variant |
| D009203 | Myocardial Infarction |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
| D007238 | Infarction |
| D007511 | Ischemia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009336 | Necrosis |
| D002637 | Chest Pain |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
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