To evaluate the lower limb alignment following total knee arthroplasty (TKA) performed with fully disposable patient-specific instrumentation versus conventional, versus patient specific instrumentation.

The investigators performed a controlled multicenter trial comparing the clinical and radiologic results and resources consumption of primary TKA using patient-specific cutting guides (PSCG) versus conventional instrumentation (CI), and compared the results to those obtained with a fully disposable patient-specific instrumentation (PSCG-D).

Inclusion Criteria:

• patients aged between 18 and 85 years
• able to understand information
• affiliated to social security

Exclusion Criteria:

• active or suspected sepsis
• tumor around the knee
• previous partial or total knee replacement
• extra-articular deformation requiring osteotomy around the knee in conjunction with TKA
• social situation that could impair follow-up