Dendritic Cells-Derived Exosomes in Human Sepsis

A Cohort Study to Investigate the Impacts of Peripheral Blood Dendritic Cells-Derived Exosomes at Early Phase on the Prognosis in Human Sepsis

The amount of peripheral blood exosomes has been confirmed to change in the endotoxin-induced infection. The primary objectives of this study are to compare the changes of peripheral blood dendritic cell-derived exosomes in the patients with sepsis and the healthy controls.

This is a prospective, single-centered, clinical cohort study.

Inclusion Criteria:

• Patients were selected with the diagnostic standard "Sepsis 3.0".
• Healthy volunteers do not have serious illness.

Exclusion Criteria:

• Patients or volunteers do not agree to provide written informed consent and / or can not be legally authorized to provide informed consent.
• Patients give up treatments.
• Patients or volunteers withdrew from the study.