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The primary goal of this investigation is to determine if lipid based artificial tear supplementation has an impact on contact lens discomfort (CLD).
Contact lens discomfort (CLD) is the most common cause of discontinuing contact lens wear. Despite years of research and innovations in technology, CLD remains highly prevalent, and thus it is a major concern for patients and practitioners. Studies suggest that meibomian gland dysfunction (MGD) is a cause of CLD. Several lipid-based artificial tears have recently been designed to address dry eye associated with MGD. In this study, the investigators examine if the benefits of lipid based artificial tears extend to improving contact lens comfort. Studies have demonstrated some usefulness of non-lipid based tear supplements in the management of contact lens discomfort. However, the relief was moderate and short-term. To date, no study has examined the impact of lipid based artificial tears on contact lens discomfort. In this study, the investigators will address this gap in knowledge.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Lipid based artificial tears | Active Comparator | Patients use lipid based artificial tears |
|
| Non-lipid based artificial tears | Active Comparator | patients use non-lipid based artificial tears |
|
| Saline | Placebo Comparator | patients use saline |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Systane Balance eye drops | Other | Propylene Glycol 0.6% Over the counter lipid based artificial tears. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Contact Lens Discomfort Questionnaire | CLDEQ Questionnaire will be used to quantify contact lens discomfort | 1 months |
| Measure | Description | Time Frame |
|---|---|---|
| Fluorescein tear break-up time | Fluorescein will be instilled in the conjunctival sac to assess tear break-up time | 1 month |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Srihari Narayanan, OD, PhD | University of the Incarnate Word | Principal Investigator |
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| ID | Term |
|---|---|
| D015352 | Dry Eye Syndromes |
| D000080343 | Meibomian Gland Dysfunction |
| ID | Term |
|---|---|
| D007766 | Lacrimal Apparatus Diseases |
| D005128 | Eye Diseases |
| D005141 | Eyelid Diseases |
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| ID | Term |
|---|---|
| D012965 | Sodium Chloride |
| ID | Term |
|---|---|
| D002712 | Chlorides |
| D006851 | Hydrochloric Acid |
| D017606 | Chlorine Compounds |
| D007287 | Inorganic Chemicals |
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| Systane Contacts eye drops | Other | Hydroxypropyl methycellulose over the counter non-lipid based artificial tears |
|
| saline | Other | Saline - no brand name |
|
| D017670 |
| Sodium Compounds |