Intravenous Immunoglobulin in Prevention of Preterm Neonatal Sepsis

Effect of Intravenous Immunoglobulin in Prevention of Preterm Neonatal Sepsis

Majority of healthcare authorities believe that due to the methodological weakness and small number of patients in conducted therapeutic trials, the evidences are insufficient to support the efficacy of intravenous immunoglobulin (IVIG) in prevention of preterm neonatal sepsis. The objective of this research is to determine the effect of intravenous immunoglobulin in prevention of preterm neonatal sepsis.

Inclusion Criteria:

• Born alive before 37 weeks of pregnancy (preterm neonates)
• Under 2500 g at birth

Exclusion Criteria:

• lethal anomaly
• congenital heart disease
• TORCH infection
• severe asphyxia