Role of 'Pentoxifylline and or IgM Enriched Intravenous Immunoglobulin in the Treatment of Neonatal Sepsis'

Phase 4 Study of Role of 'Pentoxifylline and or IgM Enriched Intravenous Immunoglobulin in the Treatment of Neonatal Sepsis'

The investigators aim is to investigate whether adjuvant Pentoxifylline , IgM enriched IVIG or Pentoxifylline plus IgM-enriched IVIG reduced mortality from Neonatal sepsis.

Inclusion Criteria::

• All infants thought/diagnosed to have late or early onset sepsis.

Exclusion Criteria:

• Pentoxifylline or Pentaglobin has already been given
• Pentoxifylline or Pentaglobin is thought to be needed or contra-indicated
• Major congenital anomaly
• Intraventricular hemorrhage (Grade 3 veya 4)
• Congenital infections
• Inborn errors of metabolism