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Waterpipe is a tool for smoking tobacco, which is thought to be less harmful than cigarette. Unfortunately, there aren't adequate studies about its harms to health that are threatening the young generation all over the world today. The objective of this study was to show the carbon monoxide (CO) levels in waterpipe smokers' breaths, whether can be used or not to reflect the changes of oxidative stress for this reason to predict harmful effects on the pulmonary functions.
Waterpipe or hookah uses a different kind of tobacco, which is available in most Balkan countries, Middle East and South Asia. Popularity of smoking waterpipe among European, Canadian, and American young people has shown a dramatic rise over the past decade. The growing popularity of waterpipe use among U.S. teens and adults is evidenced by media reports and the recent rapid proliferation of waterpipe establishments (bars, cafes, or restaurants) in large cities and near college campuses. Typical waterpipes have the following components; a bowl where the tobacco is placed and heated, usually with burning embers or charcoal, a vase or smoke chamber which is partially filled with water, a pipe or stem connecting the bowl to the vase by a tube that carries the smoke down into the water, and a hose with a mouthpiece through which the smoke is drawn from the vase. As the smoker inhales, the tobacco smoke is sucked down from the bowl and then bubbles up through the water into the air of the smoke chamber and then through the hose to the smoker. At the end of a smoking session, the dirty water is thrown away and the waterpipe vase is refilled for the next user. Although each smoking session generally lasts about 45 to 60 minutes, it can also continue for several hours.
There is a misconception about smoking waterpipe that it is less harmful than cigarettes, and that's why smoking waterpipe is dramatically increasing especially among young people. While the adverse effects of smoking cigarette are widely described, there are just a few investigations about waterpipe and its effects. This study was designed to investigate the effects of smoking waterpipe on pulmonary functions and oxidative stress parameters.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Waterpipe smokers group | Experimental | Three waterpipe cafes located in Ankara were visited. 50 waterpipe smokers aged 18-40 years, enrolled in the study and created the working group. At the same time, there were also cigarette smokers among these people. Breath carbon monoxide, pulmonary function tests were performed both before and after smoking waterpipe and parameters of oxidative stress and antioxidant status were measured in blood samples after smoking waterpipe. |
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| Control group | Active Comparator | The control group consisted of 50 people of the same age and sex, who had never smoked neither cigarette nor waterpipe. Breath carbon monoxide, pulmonary function tests were performed and parameters of oxidative stress were measured in blood samples. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Breath carbon monoxide | Procedure | Breath carbon monoxide measurement. |
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| Measure | Description | Time Frame |
|---|---|---|
| Breath Carbon Monoxide Level | Levels of CO in breath will be measured in either waterpipe smokers or control group. | Up to 4 months |
| Measure | Description | Time Frame |
|---|---|---|
| A spirometric Test; FEV1 (Forced Expiratory Volume in One Second) Measurement. | FEV1 Will Be Measured To Evaluation of Deterioration Levels of Pulmonary Functions in Either Waterpipe Smokers or Control Group. | Up to 4 months |
| A spirometric Test; FVC (Forced Vital Capacity) Measurement. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ozcan Erel, Prof. M.D. | Ankara Yildirim Beyazit University, Medical School, Director of Biochemistry Department, Ankara, Turkey | Study Director |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 18030938 | Result | Mokdad AH, Warren CW. As if cigarettes were not enough, here comes narghile. A commentary on an article by Yunis et al. in IJPH 52/4. Int J Public Health. 2007;52(5):263-4. doi: 10.1007/s00038-007-0221-6. No abstract available. | |
| 20888700 | Result | Maziak W. The global epidemic of waterpipe smoking. Addict Behav. 2011 Jan-Feb;36(1-2):1-5. doi: 10.1016/j.addbeh.2010.08.030. Epub 2010 Oct 8. |
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| ID | Term |
|---|---|
| D000073867 | Water Pipe Smoking |
| D000073865 | Cigarette Smoking |
| ID | Term |
|---|---|
| D000073868 | Pipe Smoking |
| D012907 | Smoking |
| D001519 | Behavior |
| D000073869 | Tobacco Smoking |
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| ID | Term |
|---|---|
| D012143 | Respiratory Physiological Phenomena |
| D018384 | Oxidative Stress |
| ID | Term |
|---|---|
| D002943 | Circulatory and Respiratory Physiological Phenomena |
| D008660 | Metabolism |
| D013312 | Stress, Physiological |
| D010829 | Physiological Phenomena |
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| Pulmonary function tests. | Procedure | Measurement of lung functions by blowing through a tube which measures flow and volumes of participant's lungs. |
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| Oxidative stress and antioxidant status. | Procedure | Measurement of parameters of oxidative stress and antioxidant status in blood samples. |
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FVC Will Be Measured To Evaluation of Deterioration Levels of Pulmonary Functions in Either Waterpipe Smokers or Control Group. |
| Up to 4 months |
| A spirometric Test; FEV1/FVC (Forced Expiratory Volume in One Second/Forced Vital Capacity) Measurement. | FEV1/FVC Will Be Measured To Evaluation of Deterioration Levels of Pulmonary Functions in Either Waterpipe Smokers or Control Group. | Up to 4 months |
| A spirometric Test; PEF (Peak Expiratory Flow) Measurement. | PEF Will Be Measured To Evaluation of Deterioration Levels of Pulmonary Functions in Either Waterpipe Smokers or Control Group. | Up to 4 months |
| A spirometric Test; FEF25-75 (Forced Expiratory Flow in 25-75%) Measurement. | FEF25-75 Will Be Measured To Evaluation of Deterioration Levels of Pulmonary Functions in Either Waterpipe Smokers or Control Group. | Up to 4 months |
| Plasma TAS (Total Anti-Oxydant Status) Measurement. | To Assessment of Anti-Oxidant Status: TAS Levels in Plasma Will Be Measured in Either Waterpipe Smokers or Control Group. | Up to 4 months |
| Plasma TOS (Total Oxydative Stress) Measurement. | To Assessment of Oxidative Stress: TOS Levels in Plasma Will Be Measured in Either Waterpipe Smokers or Control Group. | Up to 4 months |
| Plasma OSI Measurement. | To Assessment of Antioxidant Status: TAS (Total Anti-oxydative Status) Levels in Plasma Will Be Measured in Either Waterpipe Smokers or Control Group. | Up to 4 months |
| Plasma PON (Paraoxonase) Measurement. | To Assessment of Antioxidant Status: PON Levels in Plasma Will Be Measured in Either Waterpipe Smokers or Control Group. | Up to 4 months |
| Plasma sPON (Stimulated Paraoxonase) Measurement. | To Assessment of Antioxidant Status: sPON Levels in Plasma Will Be Measured in Either Waterpipe Smokers or Control Group. | Up to 4 months |
| Plasma ARES (Arylesterase) Measurement. | To Assessment of Arylesterase Activity: ARES Levels in Plasma Will Be Measured in Either Waterpipe Smokers or Control Group. | Up to 4 months |
| 15564614 | Result | Maziak W, Ward KD, Afifi Soweid RA, Eissenberg T. Tobacco smoking using a waterpipe: a re-emerging strain in a global epidemic. Tob Control. 2004 Dec;13(4):327-33. doi: 10.1136/tc.2004.008169. |
| 20457679 | Result | Dugas E, Tremblay M, Low NC, Cournoyer D, O'Loughlin J. Water-pipe smoking among North American youths. Pediatrics. 2010 Jun;125(6):1184-9. doi: 10.1542/peds.2009-2335. Epub 2010 May 10. |
| 12235470 | Result | Shafagoj YA, Mohammed FI. Levels of maximum end-expiratory carbon monoxide and certain cardiovascular parameters following hubble-bubble smoking. Saudi Med J. 2002 Aug;23(8):953-8. |
| D064424 |
| Tobacco Use |