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The purpose of this clinical study is to investigate the effect of drinking a sugar-sweetened beverage along with a meal on insulin concentrations and, glucose and lipid metabolism, in overweight and obese subjects, during a 10-hour visit.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 - Snack | Other | Each subject will consume 6 beverages with varying sugar content at lunch (500 ml) and with a snack in the afternoon (330 ml). The 6 beverages (Test product A, Test product B, Test product C, Test product D, Control product E and Comparative product F) will correspond to the 6 interventions. |
|
| 2 - No snack | Other | Each subject will consume 6 beverages with varying sugar content only at lunch (500 ml). The 6 beverages (Test product A, Test product B, Test product C, Test product D, Control product E and Comparative product F) will correspond to the 6 interventions. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Control product E | Other | Plain water |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Mean difference in maximum increment value of insulin concentration during first afternoon phase between each test product and the comparative product | 6 days (with 17 time points on each day) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jeanne BOTTIN, PhD | Danone Research, Palaiseau, France | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Eurofins Optimed | Gières | Auvergne-Rhône-Alpes | 38610 | France |
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| Test product A |
| Other |
Beverage with no sugar but sweetener |
|
| Test product B | Other | Beverage with 22 g/L sugar and sweetener |
|
| Test product C | Other | Beverage with 33 g/L sugar and sweetener |
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| Test product D | Other | Beverage with 47 g/L sugar and sweetener |
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| Comparative product F | Other | Beverage with 98 g/L sugar |
|
| ID | Term |
|---|---|
| D050177 | Overweight |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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