The primary objective of this study is to assess the effects of clopidogrel on the PK of K-877 in healthy adult subjects.

Inclusion Criteria:

• Subject provides written informed consent before any study-specific evaluation is performed;
• Subject is a healthy adult male or female volunteer between the ages of 18 and 45 years, inclusive at screening;
• Subject has a BMI of 18 to 30 kg/m², inclusive;
• Subject has hematology, serum chemistry, and urinalysis test results within the reference ranges, or results that do not show clinically significant abnormalities, as judged by the Investigator at screening and check-in;

Exclusion Criteria:

• Subject is a woman who is pregnant or breastfeeding;
• Subject has clinically significant abnormalities in the screening or check-in assessments;
• Subject has current or history of clinically significant coagulation, bleeding, or platelet disorders;
• Subject or a family member of the subject has a history of coagulation or bleeding disorders or reasonable suspicion of vascular malformations, including aneurysms;