The purpose of this study is to assess the effects of K-877 on the pharmacodynamics and the pharmacokinetics of warfarin in healthy adults volunteers.

Inclusion Criteria:

• Subject provides written informed consent before any study specific evaluation is performed.
• Subject is a healthy adult male or female volunteer between the ages of 18 and 45 years, inclusive.
• Subject has a body mass index of 18 to 30 kg/m², inclusive.

Exclusion Criteria:

• Subject has clinically relevant abnormalities in the screening or check in assessments.
• Subject has clinically significant out-of-range PT, INR, activated partial thromboplastin time, fibrinogen, protein C, or protein S.
• Subject has abnormal prolongation of skin bleeding time at Screening.