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IUD can cause pain and discomfort in several ways: Use of the tenaculum to grasp the cervix and straighten the uterus for proper insertion; trans-cervical actions including measuring uterine depth, inserting the IUD insertion tube, and removing the tube; and placement of the device in the uterus.
To minimize the discomfort and the hazards of an IUD insertion, several measures have been proposed including NSAIDs, anxiolytics, and local anesthetics in the form of intracervical gel, cervical and para-cervical block, but there have not done enough studies about their effectiveness. According to the review published in the Cochrane, non-steroidal anti-inflammatory drugs and misoprostol are not effective on reducing an IUD insertion pain.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ketoprofen | Experimental | women will take one tablet 150 mg one hour before the procedure |
|
| Placebo | Placebo Comparator | women will take one placebo tablet one hour before the procedure |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ketoprofen | Drug | oral non-steroidal antiinflammatory drug |
|
| Measure | Description | Time Frame |
|---|---|---|
| Mean pain score during IUD insertion | 5 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ahmed Abbas | Assiut | Cairo Governorate | 002 | Egypt |
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| ID | Term |
|---|---|
| D007660 | Ketoprofen |
| ID | Term |
|---|---|
| D010666 | Phenylpropionates |
| D000146 | Acids, Carbocyclic |
| D002264 | Carboxylic Acids |
| D009930 | Organic Chemicals |
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| placebo | Drug |
|