Forced Oscillations for Diagnosis Help in Bronchiolitis Obliterans Syndrome in Post Bone Marrow Transplantation

Functional Evaluation of Distal Airways by Forced Oscillations: Diagnosis Help in Bronchiolitis Obliterans Syndrome in Post Bone Marrow Transplantation

A study to evaluate the role of forced oscillations in diagnosis of bronchiolitis obliterans syndrome in patients after bone marrow transplantation. The force oscillations technique will be compared with classical spirometry.

Inclusion Criteria:

• Patients over 18 years
• Bone marrow or hematopoietic stem cells transplantation for more than 100 days
• Clinical stability
• Patients affiliated to a social security system
• Patients having given his (her) written consent.

Exclusion Criteria:

• Bronchiolitis Obliterans already diagnosed
• Unresolved Respiratory infection
• Unresolved mechanical complication (pneumothorax, effusions)
• Medicinal pneumopathy
• Inability to perform pulmonary function tests