Study of the Influence of the Expression of the Calcium-sensitive Receptor (CaSR) by Monocytes in the Synovial Liquid on Structural Alterations in Patients Diagnosed With Rheumatoid Arthritis in the Previous Two Years

Study of the Influence of the Expression of the Calcium-sensitive Receptor (CaSR) by Monocytes in the Synovial Liquid on Structural Alterations in Patients Diagnosed With Rheumatoid Arthritis in the Previous Two Years

Rheumatoid arthritis (RA) is the most frequent form of chronic inflammatory rheumatism in adults. The erosive damage influences the functional prognosis in patients with RA. At present, there are no sufficiently sensitive and specific predictive markers of erosive damage.

Inclusion Criteria:

• Patients consulting in the Department of Rheumatology at Amiens University Hospital
• Age ≥ 18
• RA meeting the 2010 ACR/EULAR criteria
• Less than 2 years of RA progression
• Effusion in at least 1 joint

Exclusion Criteria:

• Inability to give informed consent
• Ongoing pregnancy
• Previous treatment with an anti-osteoporosis medication
• Intra-articular corticoid or hyaluronic acid injection in the previous 6 months
• Coagulation disorders preventing arthrocentesis
• Incarceration or legal guardianship